Drrf

Drrf


One class of these factors comprises zinc finger proteins of which Sp1 is a prototypical example, having three Cys-2—His-2 zinc finger motifs 1. Central dopaminergic neurotransmission is crucial for normal brain function, and its aberrations are intricately involved in several neuropsychiatric disorders. For example, the D2 gene promoter is under strong negative control D1A probes were generated as described After determining nonsaturating concentrations of reporter plasmids in the appropriate cell lines, the indicated amounts of test plasmids were used. Sp1, Sp3, and Sp4 bind to the same recognition sequence GC boxes with similar affinities 3 , 4.

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Drrf


One class of these factors comprises zinc finger proteins of which Sp1 is a prototypical example, having three Cys-2—His-2 zinc finger motifs 1. Central dopaminergic neurotransmission is crucial for normal brain function, and its aberrations are intricately involved in several neuropsychiatric disorders. For example, the D2 gene promoter is under strong negative control D1A probes were generated as described After determining nonsaturating concentrations of reporter plasmids in the appropriate cell lines, the indicated amounts of test plasmids were used. Sp1, Sp3, and Sp4 bind to the same recognition sequence GC boxes with similar affinities 3 , 4. Drrf

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  1. Underlined bases in the wild-type sequence were replaced with bases shown in parentheses in the mutant probes.

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